Employers that have employees who handle organophosphate pesticides in an agricultural plant production operation must have a signed written agreement from a doctor for medical supervision if _____________.

The requirement for a signed written agreement from a doctor for medical supervision is specifically tied to the regular handling of organophosphate pesticides, particularly those that bear the signal words "DANGER" or "WARNING." This classification indicates a higher level of toxicity and potential health risks associated with these pesticides. Regular exposure to such hazardous chemicals necessitates medical supervision to monitor the health of employees and to ensure their safety while working with these substances.

Medical supervision is essential because organophosphates can have significant effects on the nervous system and other bodily functions. Therefore, monitoring is critical to prevent any adverse health outcomes. The law mandates that employers take proactive steps to safeguard their employees when they are in an environment with such potential risks.

In this context, while there may be various concerns related to age, any pesticides, or general handling practices, the specific focus on organophosphate pesticides marked with these signal words is what triggers the requirement for medical supervision. This approach ensures that the necessary health precautions are taken when handling particularly hazardous pesticides.